ABSTRACT
@#Introduction: COVID-19 disease is currently pandemic, and its prevalence in Saudi Arabia is concerning. The SARSCoV-2 virus primarily affects the lungs, but it also affects the haematopoietic system. The atypical lymphocytes on peripheral blood film that have a distinct morphological appearance were of particular interest in this study. Our goal was to see a link between atypical lymphocytes and COVID-19 patient mortality. Methods: This four-month single-centered prospective descriptive study was conducted in Makkah, Saudi Arabia. COVID-19 patients of both genders were randomly selected based on inclusion criteria. The data from the patient’s electronic medical record was extracted. All patients’ peripheral blood film parameters were recorded on days 3, 7, and 14 after admission. The statistical data was analysed using SPSS version 23. The Fisher’s exact test was used to determine the relationship with mortality. A p value of 0.05 was considered significant. Results: The total number of cases enrolled in the study was 226. The patients’ average age was 58 years (SD 0.5289). On the third day of admission, 88.2 % of patients with COVID-19 had atypical lymphocytes, with a mean of 2.35 ± 0.927. A significant correlation (p < 0.001) exists between atypical lymphocytes decreasing percentage number on the 3rd, 7th, and 14th days of admission and death. Conclusion: The decrease in the number of atypical lymphocytes on peripheral blood film has a significant association with the patients’ mortality. This fact can be used to develop a tailored management strategy based on the observation of peripheral blood film.
ABSTRACT
Background: Stroke is the second leading cause of death worldwide. Defined by the WHO as 'Rapidly developing clinical signs of focal or global disturbance of cerebral function with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than vascular origin'. It is a major complication of hypertension
Objectives: To evaluate the personal and clinical characteristics of stroke patients
Setting: Salmaniya Medical Complex, Bahrain
Design: A Retrospective Cross-Sectional Study. I
Method: All patients diagnosed and admitted between 1 January 2010 and 31 December 2010 were included. One hundred eighty-three patients were included in the study
Personal and clinical data were documented. Data was entered and analyzed using SPSS program version 17
Result: Ischemic stroke was the most common, 115 [62.8%]
The majority of patients were males, 129 [70.5%]
The most notable outcome is the rehabilitated patients, 74 [40.4%]
One hundred sixty-six [90.7%] patients did not suffer confusion, whereas 84 [45.9%] had impaired speech and 77 [42.1%] had right-sided numbness and weakness
Conclusion: The most common type of stroke was the ischemic stroke, 115 [62.8%]
The most common symptom was weakness, 147 [80.3%]
The most common risk factor was hypertension, 136 [74.3%] and the most common outcome was rehabilitation, 74 [40.4%]